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KMID : 0363219770150020191
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Korean Journal of Dermatology
1977 Volume.15 No. 2 p.191 ~ p.195
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Clinical Trials of Frason^® on Various Dermatosis
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玄鍾鳴/Hyun, Jong Myung
李蘭姬/朴洋子/金辰澤/Lee, Nan Hee/Park, Yang Ja/Kim, Jin Tack
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Abstract
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Esperson^(®) a new topical steroid ointment containing 0.05 % 17-Desoxymethasone, was used in several kinds of dermatoses. Framycetin which was isolated and identified by the research organisation of Roussel Laboratories (SOFRAPEN) in 1950 from culture broths of a strain of Streptomyces species is a wide spectrum antibiotics on various bacterial infectious diseases.
Total 50 patients including 10 cases of 2ndary infected Atopic dermatitis, 10 of infected Contact dermatitis, 6 of infected Seborrheic dermatitis, 7 of infected Neurodermatitis, 3 of infected Chronic dermatitis, 5 of Impetigo, 2 of infected Nummular eczema, 2 of infected Infantile eczema, 1 of infected Intertrigo, 1 of Eczematoid Otitis externa, 1 of 2nd degree ´Burn, 1 of infected Pruritis ani, 1 of infected Insect bite. were treated with Frason (0.05 % 17-desoxymethasone & 0.5 % Framycetin combination).
Among these 50 patients, we observed excellent effects in 7 patients (14%), good effect in 29 patients (58 %), fair effect in 10 patients (20%), Totally 36 patients (720/0´) revealed excellent to good therapeutic effects on their skin conditi ors after unoccluded application of Frason^(®). 3 times daily for about 14 days.
There was no side effect in all subjects after application of Esperson-F.
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